Luke Griffith reveals Peptide stack he believes enabled win against Felipe Pena

In the aftermath of his stunning heavyweight title victory over Felipe Pena at Who’s Number One 31, Luke Griffith has opened up about the recovery protocol that kept him competing at his peak throughout his demanding training camp.

Taking to social media, the newly crowned champion disclosed a specific combination of peptides that he credits with maintaining his physical condition during preparation for the high‑stakes bout in Austin, Texas. The stack, which Griffith captioned in his video, consisted of SLU‑PP‑332, GLOW, MOTS‑C, and BPC‑157.

“Alright, we’re going to be giving away the stack that I used to keep my body pain‑free during the Pena camp,” Griffith announced in the video, referring to his training camp focused on defeating the decorated Brazilian competitor.

Elite grapplers increasingly turn to peptide therapies for recovery and injury management. BPC‑157, perhaps the most well‑known of the compounds Griffith mentioned, has gained popularity among athletes for its purported tissue repair properties. Other peptides like MOTS‑C and SLU‑PP‑332 have become part of high‑performance discussions in biohacking circles.

Elite competitors outside grappling have been vocal too. Strongman Mitchell Hooper, for example, publicly explained his peptide stack and why he takes each compound, highlighting BPC‑157’s role in injury recovery: “BPC‑157 has gained huge traction … shows consistent positive effects for various injury types both traumatic and systematic for a plethora of soft tissues,” credited with helping him recover from a hamstring injury faster than expected. Source

Similarly, UFC commentator and podcaster Joe Rogan has openly discussed his use of peptides like BPC‑157 and TB‑500 for recovery from injuries — including an Achilles issue — and emphasized how he administered them for localized effect: “BPC‑157 and TB‑500 — that’s it … I think local is the way to go … It’s like why not?”

Dr. Andrew Huberman, neuroscientist and podcast host, has also weighed in on the broader peptide conversation. In discussing peptide science he described peptides as “a new kind of wedge in between supplements and prescriptions,” noting some stimulate growth hormone release and aid recovery. On BPC‑157 specifically, Huberman shared his own experience: “It promotes healing of tissues … Two injections of BPC157 — gone,” referring to resolution of an L5 compression issue.

Even outside the fitness world, public figures have acknowledged peptide use during physical rehabilitation. Actor Jeremy Renner detailed his recovery after a near‑fatal accident, noting that his regimen included “peptide injections” among therapies like IV drips and physical therapy in his healing journey.

Griffith’s transparency about his regimen arrives on the heels of a career‑defining performance. The American grappler needed less than four minutes to submit Pena with a rear‑naked choke, capturing the vacant heavyweight championship in the process. The victory was especially meaningful given that Pena had previously defeated Griffith twice by submission, making the mental hurdle perhaps as significant as the physical one.

While some controversy emerged regarding how long Griffith maintained the submission, the champion clarified he was simply waiting for the referee’s official intervention.